Huoliss innovative product

STATEMENT
from
Prof. Dr. Krum Vladimirov Nedelkov, PhD
Faculty of Veterinary Medicine,
Trakia University, Stara Zagora
Regarding: the use of hydrolysed collagen in pet foods.

1. Information about proteins
A protein is a macromolecule consisting of about twenty different amino acids connected by peptide bonds. After being consumed by animals through the diet, proteins are hydrolysed to small peptides (di — and tripeptides) and free amino acids by enzymatic proteases and oligopeptidase in the small intestine (Wu, 2013). Enzymatic hydrolysis similar to that used in the production of pure amino acids for the pharmaceutical industry leads to the formation of stable protein sources composed exclusively of free amino acids and a small number of oligopeptides with very low molecular weight (Hou et al., 2013).

2. Results from the laboratory analysis
The laboratory testing of the hydrolysed animal collagen from pig skins of “Leather Art” Ltd. shows a high content of essential/indispensable amino acids such as Arginine (0.751 g/100g), Lysine (0.604 g/100g), Leucine (0.567 g/100g), Phenylalanine (0.342 g/100g), Threonine (0.319 g/100g) and others. Essential amino acids cannot be synthesised from other compounds, so they must be present in food. The hydrolysed collagen of “Leather Art” Ltd. would provide enough essential amino acids, whose synthetic analogues are extremely expensive and of far lower digestibility. In addition, the laboratory analysis of the hydrolysed collagen of “Leather Art” Ltd. shows an extremely high content of replaceable amino acids such as Glycine (2.29 g/100g), Proline (1.35 g/100g), HydroxyProline (0.945 g/100g) , Alanine (1.03 g/100g), Aspartic acid (0.863 g/100g) and others, which are in an easy and convenient form for absorption and assimilation by animals.

3. Use in pet foods
Diets with protein hydrolysates, and hydrolysed collagen in particular, became extremely popular in specialty clinical diets for pets as early as about 15 years ago. Diets containing hydrolysed collagen can significantly reduce adverse allergic reactions and reduce sensitivity to certain foods in dogs. Also, the use of hydrolysed collagen has a beneficial effect on some acute degenerative diseases in pets such as osteoarthritis. Imaging findings of the knee joint show that orally administered collagen peptides have great potential to stimulate proteoglycan synthesis in knee joints in mild forms of osteoarthritis (McAlindon et al., 2011). Previous research has shown that a reduction in lameness and increased mobility in dogs after treatment with collagen peptides is associated with significantly reduced plasma levels of MMP-3, which is involved in collagen degradation (Weide, 2004). Hydrolysed animal collagen also plays an important role in improving the palatability of pet foods. The hydrolysis process breaks down the proteins into smaller peptides that have the property of reducing bitterness and increasing the palatability and flavour of food. The improvement in the taste and aroma of the feed increases the animal’s desire for higher consumption, which leads to better nutrition and overall health. In addition, hydrolysed animal collagen can be tailored to specific dietary needs, ensuring that pets will receive optimal nutrition without compromising the taste or the texture of the food. This is particularly useful for dogs and cats with food sensitivities or allergies that require the preparation of specialised clinical/veterinary diets.

I recommend the use of the hydrolysed animal collagen of the company «Leather Art» Ltd. in maintenance foods for pets, as well as in special diets formulated to improve joint metabolism in osteoarthritis or other joint problems, especially after orthopaedic operations.
March 25, 2024 Signed by Prof. Dr. Krum Vladimirov Nedelkov, PhD
Stara Zagora